Signaling to muscle satellite cells

satellite cells contribution to exercise mediated muscle hypertrophy and repair

satellite cells (scs) are the most abundant skeletal muscle stem cells. they are widely recognized for their contributions to maintenance of muscle mass, regeneration and hypertrophy during the human life span. these cells are good candidates for cell therapy due to their self-renewal capabilities and presence in an undifferentiated form. presently, a significant gap exists between our knowledg...

Isolation and optimization of mice skeletal muscle satellite cells using preplating method and culture media substitution

Introduction: Satellite cells are known as the main regenerative cell type in skeletal muscles. Our study established a modified digestion and preplating method for the isolation of slow or weak adherent cells for the enrichment of satellite cells. Low-survival rate of these primary stem cells prompted us to address whether cell culture medium substitution might change cell viability status. M...

Satellite Cells Contribution to Exercise Mediated Muscle Hypertrophy and Repair

Satellite cells (SCs) are the most abundant skeletal muscle stem cells. They are widely recognized for their contributions to maintenance of muscle mass, regeneration and hypertrophy during the human life span. These cells are good candidates for cell therapy due to their self-renewal capabilities and presence in an undifferentiated form. Presently, a significant gap exists between our knowledg...

Sources for skeletal muscle repair: from satellite cells to reprogramming

Skeletal muscle regeneration is the process that ensures tissue repair after damage by injury or in degenerative diseases such as muscular dystrophy. Satellite cells, the adult skeletal muscle progenitor cells, are commonly considered to be the main cell type involved in skeletal muscle regeneration. Their mechanism of action in this process is extensively characterized. However, evidence accum...

Muscle Satellite Cells and Duchenne Muscular Dystrophy